Allergic Reaction due to Anti-Tuberculosis Drugs, How to Manage?

Tuberculosis (TB) still becomes a significant health problem in Indonesia. The first-line anti-tuberculosis drug (ATD) is the most effective TB drug, but it can have some side effects. One of them allergic skin reactions that affect patient's compliance. Allergic due to ATD are found 4-6% cases and third frequent effect after gastrointestinal liver function disorder. All cause reactions. be mild, such as itching reddish rashes, severe life-threatening anaphylactic shock, Steven Johnson Syndrome (SJS), Toxic Epidermal Necrotic (TEN). important things management identifying stopping drugs. It includes challenge desensitization causing drug. Desensitization must distinguished from or provocation tests, which diagnostic tools. proper improve compliance outcomes.